作者: Stefan White , Andrew Sinclair
DOI: 10.1007/978-3-642-22964-0_1
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摘要: Disorders of Sex Development (DSD) are congenital conditions where the development chromosomal, gonadal or anatomical sex is atypical. In most cases this due to a breakdown gene regulatory networks that responsible for appropriate gonad development. Studies in humans and mice have identified number genes play critical roles testis ovary chapter we review some key involved describe how defects affecting these result DSD.