Lanostane triterpenoids and sterols from Antrodia camphorata.
作者： Hui-Chi Huang , Chih-Chuang Liaw , Hsin-Ling Yang , You-Cheng Hseu , Hsiou-Ting Kuo
DOI: 10.1016/J.PHYTOCHEM.2012.08.011
关键词:
摘要: Four lanostane triterpenes, 3,7,11-trioxo-5α-lanosta-8,24(E)-dien-26-oic acid, methyl 11α-3,7-dioxo-5α-lanosta-8,24(E)-dien-26-oate, 3,7,11,12,15,23-hexaoxo-5α-lanost-8-en-26-oate, and ethyl two sterols, (14α,22E)-14-hydroxyergosta-7,22-diene-3,6-dione a steroid named as camphosterol A were isolated from mixture of fruiting bodies mycelia solid cultures Antrodia camphorata. The ¹H ¹³C NMR spectra all compounds fully assigned using combination 2D experiments, including COSY, HMQC, HMBC NOESY sequences. Six evaluated for cytotoxicity against several human tumor cell lines, which has moderate activity.
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