New Treatment Modalities for Basal Cell Carcinoma
作者： E. Stockfleth , W. Sterry
DOI: 10.1007/978-3-642-59410-6_31
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摘要: Basal cell carcinoma (BCC) is a subtype of nonmelanoma skin cancer (NMSC), potentially fatal disease linked to overexposure the sun during childhood. BCC has been associated with UV-induced mutations PTC and p53 tumor suppressor genes, polymorphisms in melanocortin-1 receptor XPD genes. Mortality rates due are low, but its increasing incidence prolonged morbidity means costly treat. Early recognition effective treatment therefore important, reduce lighten economic burden management. This paper reviews current treatments for BCC, including excision curettage, electrodessication, surgery, cryosurgery, radiotherapy, 5-fluorouracil intralesional/perilesional cytokines. It also deals two new modalities, photodynamic therapy imiquimod 5% cream, an immune response modifier that effectively resolves lesions.
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