Pretransplantation combined therapy with plasmapheresis and rituximab in a second living‐related kidney transplant pediatric recipient with a very high risk for focal segmental glomerulosclerosis recurrence

摘要: Chikamoto H, Hattori M, Kuroda N, Kajiho Y, Matsumura Fujii Ishizuka K, Hisano Akioka Nozu Kaito Shimizu M. Pretransplantation combined therapy with plasmapheresis and rituximab in a second living-related kidney transplant pediatric recipient very high risk for focal segmental glomerulosclerosis recurrence. Pediatr Transplantation 2011. © 2011 John Wiley & Sons A/S. Abstract:  Prophylactic PP can provide some protection against post-transplantation recurrences of FSGS, but it cannot prevent all cases. Therefore, new preventive therapies are needed. We report on 7.9-yr-old girl treated pretransplantation prophylactic consisting four sessions one dose before KTX. The patient had FSGS recurrence because this occurred after the first During 36 months since transplantation, she has no evidence proteinuria or significant infectious complications. Although our experience is too preliminary to draw any generalizable conclusions, might be possible option prevention high-risk recipients undergoing living-donor KTXs.