Efficacy and adverse effects of patient-controlled epidural or intravenous analgesia after major surgery.
作者： Ping-Wing Lui , Chinsan Liew , Jenkin S Hu , Yun-Hui Teng , Shen-Kou Tsai
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摘要: BACKGROUND The purpose of this retrospective study was to determine whether epidural fentanyl-bupivacaine patient-controlled analgesia (PCA) more efficacious and had fewer adverse effects than or intravenous morphine PCA. METHODS We retrospectively retrieved data from 859 patients (mean age 64+/-7 years) who received continuous medication, either PCA, PCA for postoperative pain control after major elective surgery 1999 2000. Pain assessed postoperatively using a verbal analogue scale (VAS, 0-10) during rest, mobilization, coughing. Adverse including nausea, vomiting, pruritus, urinary retention, sedation, motor block, respiratory depression ( 86%) fentanyl combined with bupivacaine, experienced good relief 0-3) Nonetheless, greater satisfaction overall (PRS = 4) did those (p<0.05). Nausea vomiting were most common in the group Pruritus occurred least often (p < 0.05). There no differences other events such as block among three groups. No found any patient. CONCLUSIONS Patients receiving better relief, while epidurally intravenously, caused side effects. It is considered safe use surgery.
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