Prevalence of Diabetes and Impaired Glucose Tolerance and Plasma Glucose Levels in U.S. Population Aged 20–74 Yr

作者: M. I. Harris , W. C. Hadden , W. C. Knowler , P. H. Bennett

DOI: 10.2337/DIAB.36.4.523

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摘要: The prevalence of physician-diagnosed diabetes and undiagnosed impaired glucose tolerance (IGT) that meet National Diabetes Data Group (NDDG) World Health Organization (WHO) criteria have been estimated for the U.S. population aged 20-74 yr from 1976-1980 Nutrition Examination Survey. This survey included a demographic/medical history questionnaire administered in participant's home detailed examination composed physician's exam, special clinical procedures, other tests, collection blood urine specimens. Survey participants were selected 1970 census data through stratified multistage probability sampling scheme. Of 17,390 eligible residents yr, 15,357 (88.3%) participated interview are basis estimates diagnosed diabetes; 11,858 (68%) exam. A half sample 5901 examinees was to receive 75-g oral test (OGTT) performed morning after an overnight 10- 16-h fast. these examinees, valid OGTT obtained 3772 people without medical diabetes, IGT. major reasons incomplete inability attend center lack adherence fasting instructions. Despite relatively low response rates, evidence is presented on both interviewed those receiving OGTT, when adjusted 1970-1980 characteristics by age, race, sex, income, geographic location, representative population. Extrapolation indicates total 6.6% NDDG criteria, or more than 8 million with diabetes. (3.2%) almost equal previously (3.4%). Total rates increased 2.0% at age 20-44 17.7% 65-74 yr. Rates approximately sex but greater Blacks Whites. WHO (3.4%) similar rate (11.2%) twice estimate (4.6%). Both obesity parental associated significantly higher Fasting plasma insensitive 1-h 2-h post-75-g values age.

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