Functionalized Gold Nanoparticles for the Detection of C-Reactive Protein

摘要: C-reactive protein (CRP) is a very important biomarker of infection and inflammation for number diseases. Routine CRP measurements with high sensitivity reliability are highly relevant to the assessment states efficacy treatment intervention, require development sensitive, selective, fast, robust reproducible assays. Gold nanoparticles (Au NPs) distinguished their unique electrical optical properties ability conjugate biomolecules. Au NP-based probes have attracted considerable attention in last decade analysis biological samples due simplicity, selectivity. Thus, this article aims be critical constructive literature three years regarding advances made bioanalytical assays based on gold vitro detection quantification from samples. Current methods NP synthesis strategies surface modification aiming at selectivity towards highlighted.