Renin-angiotensin system as a potential therapeutic target in stroke and retinopathy: experimental and clinical evidence.
作者： Abdelrahman Y. Fouda , Sandeep Artham , Azza B. El-Remessy , Susan C. Fagan
DOI: 10.1042/CS20150350
关键词:
摘要: As our knowledge expands, it is now clear that the renin-angiotensin (Ang) system (RAS) mediates functions other than regulating blood pressure (BP). The RAS plays a central role in pathophysiology of different neurovascular unit disorders including stroke and retinopathy. Moreover, beneficial actions modulation brain retina have been documented experimental research, but not yet exploited clinically. complex with distinct interconnected components. Understanding components their under retinal pathological conditions crucial to reap benefits. aim present review provide an clinical update on treatment Combining evidence from both these allows unique opportunity move fields forward.
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