Proton magnetic resonance spectroscopic images and MRI volumetric studies for lateralization of temporal lobe epilepsy

摘要: We obtained 2D magnetic resonance (MR) spectroscopic images (MRSI) and MRI volumetric measurements (MRIV) of amygdala hippocampus in 30 consecutive patients with temporal lobe epilepsy (TLE) being evaluated for surgical treatment. Both MRSI MRIV lateralization showed good agreement the current gold standard clinical-EEG lateralization. Each exam separately correctly lateralized 25 out no false Combining both exams, could be achieved 28 patients. The two significant asymmetry had bitemporal EEG abnormalities, bilateral damage on MRSI. There was a correlation between magnitude (Pearson coefficient = 0.83; p < .0001). were normal our seizures originating outside lobes. can lateralize TLE 83% Combination modalities allows 93% Patients who cannot generally have symmetrical abnormalities; they are not incorrectly lateralized. structural chemical pathologic abnormalities seen seem to associated seizure focus, may as, or even more, reliable than few recorded predicting side from which most originate.