Prevalence, clinical predictors and diagnosis of gastro-oesophageal reflux in children with persistent respiratory symptoms.

作者: M Z Norzila , A Zulfiqar , C T Deng , B H Azizi , K Siti Mazliah

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摘要: Objectives This was a cross sectional study conducted in the Paediatric Institute among infants and children with chronic respiratory symptoms following objectives: i) to determine prevalence of gastro-oesophageal reflux persistent symptoms, ii) identify clinical predictors GOR (Gastro-oesophageal reflux) iii) assess validity abdominal ultrasound, barium oesophagogram chest radiograph diagnosing these patients. Materials methods Forty-four patients were recruited over period six months. All presenting identified. The subjected radiograph, 24-hour pH oesophageal monitoring. predictive ultrasound assessed. Twenty-four hours gold standard diagnose GOR. Results mean age 9.1 months (1-58 months). Thirty-one (70.5%) confirmed have by study. Respiratory alone not useful predict Cough had highest sensitivity 51.6%. Stridor, wheeze choking each specificity 76%. Wheeze, vomiting, stridor identified high (90-100%) when any two taken combination. Collapse/consolidation commonest radiological abnormality but low (35.5%) (53.8%). However hyperinflation on 92.3% positive value 80% Barium has (37.9%) moderate (75%) symptoms. Abdominal valid mode there three or more episodes demonstrated during screening 90.9%. i.e. 20-25%. increased 90-100% tests combination (abdominal oesophagogram). remained (10-20%). Chest did improve considered above tests. Combination as In absence monitoring, may be helpful

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