The effects of pain severity on health-related quality of life: a study of Chinese cancer patients.

作者: Xin S Wang , Charles S Cleeland , Tito R Mendoza , Martha C Engstrom , Shujun Liu

DOI: 10.1002/(SICI)1097-0142(19991101)86:9<1848::AID-CNCR29>3.0.CO;2-M

关键词:

摘要: BACKGROUND The health-related functioning of patients with cancer is compromised by several factors, including the disease process, treatment, and various symptoms that are produced both treatment. This study was designed to specify relationship between patients' pain severity their self-reported quality life. METHODS The enrolled 216 consecutive consenting adult from 2 Chinese centers pathologically-diagnosed metastatic who could understand complete self-report measures. The majority had cancer-related were receiving analgesics. version Brief Pain Inventory used assess interference pain. A translation Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36) functional status. Patients' physicians completed a form indicated characteristics cancer, Eastern Cooperative Oncology Group performance status, pain, current treatment. RESULTS Increasing associated worsening functioning, even when an estimate taken into account. correlation impairment nonlinear. health well-being no or mild significantly less impaired than moderate severe did not differ. CONCLUSIONS Pain important variable be account life outcome measures considered. well-controlled (mild) differ without Providing relief should improve status patients. Cancer 1999;86:1848–55. © 1999 American Society.

参考文章(19)
Cella Df, Tulsky Ds, Measuring quality of life today: methodological aspects. Oncology. ,vol. 4, pp. 29- 38 ,(1990)
P. A. Ganz, R. Day, J. E. Ware, C. Redmond, B. Fisher, Base-Line Quality-of-Life Assessment in the National Surgical Adjuvant Breast and Bowel Project Breast Cancer Prevention Trial Journal of the National Cancer Institute. ,vol. 87, pp. 1372- 1382 ,(1995) , 10.1093/JNCI/87.18.1372
Niels Becker, Annemarie Bondegaard Thomsen, Alf Kornelius Olsen, Per Sjøgren, Per Bech, Jørgen Eriksen, Pain epidemiology and health related quality of life in chronic non-malignant pain patients referred to a Danish multidisciplinary pain center Pain. ,vol. 73, pp. 393- 400 ,(1997) , 10.1016/S0304-3959(97)00126-7
Katherine R. Edwards, Charles S. Cleeland, Ronald C. Serlin, Tito R. Mendoza, Yoshio Nakamura, When is cancer pain mild, moderate or severe? Grading pain severity by its interference with function. Pain. ,vol. 61, pp. 277- 284 ,(1995) , 10.1016/0304-3959(94)00178-H
Martin H. Kalser, Jamie Barkin, John M. Macintyre, Pancreatic cancer. Assessment of prognosis by clinical presentation. Cancer. ,vol. 56, pp. 397- 402 ,(1985) , 10.1002/1097-0142(19850715)56:2<397::AID-CNCR2820560232>3.0.CO;2-I
John E. Ware, Cathy Donald Sherbourne, The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Medical Care. ,vol. 30, pp. 473- 483 ,(1992) , 10.1097/00005650-199206000-00002
Alfredo J. Selim, Graeme Fincke, Xinhua S. Ren, William Rogers, Austin Lee, Lewis Kazis, A Symptom-Based Measure of the Severity of Chronic Lung Disease Chest. ,vol. 111, pp. 1607- 1614 ,(1997) , 10.1378/CHEST.111.6.1607