Evaluation of esophageal motility and reflux in children treated for congenital diaphragmatic hernia with the use of combined multichannel intraluminal impedance and pH monitoring

摘要: Abstract Background Gastroesophageal reflux (GER) is frequently observed in children treated for congenital diaphragmatic hernia (CDH) at birth, as well esophageal dysmotility, that has been hypothesized to be caused by innervatory anomalies. The aim of this study evaluate GER and dysmotility young patients with CDH using pH-multichannel intraluminal impedance. Methods Thirty (17 boys 13 girls) who underwent repair between 2002 2007 a median age 5.2 years (range, 3-10 years) were included the study. All operated on subcostal laparotomy incision had left-sided defect. defect required an artificial patch (Goretex, Gore Medical, Flagstaff, AZ) 8 (27%) because its size. We described impedance parameters some specific motility studied 10 standardized swallows. Results incidence was 86%. Reflux mainly nonacidic, postprandial, short-term reached only distal esophagus. Esophageal Conclusions With use impedance, both malformations can analyzed. In CDH, impaired seems involve group, pattern probably involvement gastroesophageal junction, without significant intrinsic innervation abnormalities atresia.