Isolation of the Fundamental Polypeptide Subunits of Biological Membranes

作者: M. T. Laico , E. I. Ruoslahti , D. S. Papermaster , W. J. Dreyer

DOI: 10.1073/PNAS.67.1.120

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摘要: Abstract A group of peptides (some or all them glycopeptides), molecular weight about 5000, has been shown to be a major fraction biological membranes. These „miniproteins” have prepared from membranes human and bovine red blood cells, purified liver mitochondria, the rhodopsin-containing outer segments retinal rods. While miniproteins were found in large amounts each case, other protein components differed markedly depending on function membrane studied. This fact was particularly clear case rod where only proteins detected rhodopsin. The size miniprotein these leads us propose that play fundamental role several functions which occur as common denominators

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