Protein-bound homocyst(e)ine in patients with rheumatoid arthritis undergoing D-penicillamine treatment.
作者： Soo-Sang Kang , Paul W. K. Wong , Paul B. Glickman , Catherine M. MacLeod , Israeli A. Jaffe
DOI: 10.1002/J.1552-4604.1986.TB02978.X
关键词:
摘要: Protein-bound homocyst(e)ine was measured in the plasma of 38 nonhomocystinuric patients with rheumatoid arthritis. Nineteen them were treated orally D-penicillamine 100-1,500 mg/d for a period one month to 15 years. For these patients, mean +/- standard deviation level protein-bound 1.95 1.07 nmol/mL. In contrast, 4.72 1.11 nmol/mL 19 who had not been oral D-penicillamine. There statistically significant difference (P less than .0001) concentrations between and without therapy. Thus, it may be speculated that beneficial protecting from development thromboembolism arteriosclerosis.
sci-hub.se 参考文章(13)
C Bengtsson, Ischaemic heart disease in women. A study based on a randomized population sample of women and women with myocardial infarction in Göteborg, Sweden. Acta Medica Scandinavica. ,vol. 549, pp. 1- 128 ,(1973)
Thomas L. Perry, Shirley Hansen, Technical pitfalls leading to errors in the quantitation of plasma amino acids Clinica Chimica Acta. ,vol. 25, pp. 53- 58 ,(1969) , 10.1016/0009-8981(69)90226-5
Kenneth J. Ryan, Estrogens and atherosclerosis. Clinical Obstetrics and Gynecology. ,vol. 19, pp. 805- 816 ,(1976) , 10.1097/00003081-197612000-00008
Soo-Sang Kang, Paul W K Wong, Kay Curley, The Effect of D-Penicillamine on Protein-Bound Homocyst(e)ine in Homocystinurics Pediatric Research. ,vol. 16, pp. 370- 372 ,(1982) , 10.1203/00006450-198205000-00010
Soo-Sang Kang, Paul W K Wong, Nancy Becker, Protein-bound homocyst(e)ine in normal subjects and in patients with homocystinuria. Pediatric Research. ,vol. 13, pp. 1141- 1143 ,(1979) , 10.1203/00006450-197910000-00012
S S Kang, P W Wong, H Y Cook, M Norusis, J V Messer, Protein-bound homocyst(e)ine. A possible risk factor for coronary artery disease. Journal of Clinical Investigation. ,vol. 77, pp. 1482- 1486 ,(1986) , 10.1172/JCI112461
G H Boers, A G Smals, F J Trijbels, A I Leermakers, P W Kloppenborg, Unique efficiency of methionine metabolism in premenopausal women may protect against vascular disease in the reproductive years. Journal of Clinical Investigation. ,vol. 72, pp. 1971- 1976 ,(1983) , 10.1172/JCI111161
TAVIA GORDON, Menopause and Coronary Heart Disease Annals of Internal Medicine. ,vol. 89, pp. 157- 161 ,(1978) , 10.7326/0003-4819-89-2-157
L A Harker, R Ross, S J Slichter, C R Scott, Homocystine-induced arteriosclerosis. The role of endothelial cell injury and platelet response in its genesis. Journal of Clinical Investigation. ,vol. 58, pp. 731- 741 ,(1976) , 10.1172/JCI108520
L E Brattstrom, J E Hardebo, B L Hultberg, Moderate homocysteinemia--a possible risk factor for arteriosclerotic cerebrovascular disease. Stroke. ,vol. 15, pp. 1012- 1016 ,(1984) , 10.1161/01.STR.15.6.1012