Simultaneous long-term recording of the mechanical and intracellular electrical activity of smooth muscles

摘要: The construction and use of tissue holders that allow simultaneous long-term recordings mechanical intracellular electrical activity from a variety smooth-muscle preparations is described. permit adjustment stretch following its fixation for recording purposes. By this means microelectrodes can be kept in position despite marked changes the tissue. Since up to 2 hrs duration made, studies relationships between membrane potential evoked by drugs neurotransmitters are greatly facilitated.