Exposure to excessive fluoride during hemodialysis

作者: William J. Johnson , Donald R. Taves

DOI: 10.1038/KI.1974.64

关键词:

摘要: The safety of fluoridated community water supplies for dialysate and long-term intermittent hemodialysis has been questioned since 1965 [1]. only significant means clearing fluoride from body fluids are renal excretion incorporation into bone [2]. When is prepared with water, ion moves along a concentration gradient to blood [3, 4]. Because defective or absent in such patients, the administered during dialysis incorporated skeleton. Under these conditions, serum concentrations increase progressively, content rises above values obtained persons normal function who drink that [3–6] (the 53 LM [1 ppm] 0.7 ± 0.4 μM [mean ±SD]). Although it not established adversely affects patients maintained by hemodialysis, this possibility exists, particularly have exposed many years. This other problems associated various substances tap made deionization used common practice. Unfortunately, if deionizer improperly maintained, may actually as becomes exhausted.

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