Chromosomes and Kinetochores do More in Mitosis than Previously Thought

作者: R. Bruce Nicklas

DOI: 10.1007/978-1-4613-1037-2_2

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摘要: Chromosomes do more to promote their own distribution the daughter cells in mitosis than we thought. A role of chromosomes movement was made clear 1930’s when it recognized that a site on each chromosome — kinetochore or centromere is essential for normal and meiosis (review: Schrader, 1953). Since then, one certain has been identified: mechanical attachment spindle. Now, new aspects have revealed as well less expected chromosomal activities. My aim an informal account recent surprises followed by some remarks nature gene its evolutionary origin. More extensive reviews all but most work include Rieder (1982), McIntosh (1985), Brinkley et al. (1985)

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