A hyperspectral time resolved DOT system to monitor physiological changes of the human brain activity

作者: F. Lange , F. Peyrin , B. Montcel

DOI: 10.1117/12.2183291

关键词:

摘要: Diffuse optical tomography (DOT) is a growing area of research in the field biomedical optics and neurosciences. Over past 20 years, technical development allowed more accurate detection brain activation, both spatially calculation variations chromophores’s concentrations such as Hemoglobin, cytochrome c oxidase, etc. In particular, time resolved systems are able to distinguish between superficial layers (skin, skull) deep (brain) allowing differentiation systemic response brain. order increase accuracy brain’s activation detection, we have developed Hyperspectral Time Resolved DOT system. It composed compact supercontinuum laser within picosecond range for source part an ICCD camera coupled with imaging spectrometer part. This allows simultaneous spatial spectral dimension, well flight photons. Through information acquired by our system, we’ve been retrieve, knowledge, first spectrum physiology human activity function depth. Here present instrument show in-vivo results that demonstrating its capabilities skin’s responses during cognitive task. We also focused on Fast Optical Signal.

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