The developmental capacity of mouse oocytes that matured spontaneously in vitro is normal.
作者： Allen C. Schroeder , John J. Eppig
DOI: 10.1016/0012-1606(84)90215-X
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摘要: The aim of this project was to compare the developmental capacities mouse oocytes matured in vivo and vitro. frequencies fertilization, preimplantation development, birth live offspring after transfer morulae uteri pseudopregnant foster mothers were compared germinal vesicle stage underwent spontaneous maturation vitro, gonadotropin-induced ovulation. Both groups ova fertilized development carried out Equivalent observed for all comparisons between two oocytes. acquisition normal capacity depended on presence serum oocyte medium. expansion (mucification) cumulus oophorus not required fertilization or development. frequency lower that while denuded cells. However, when did occur these oocytes, a percentage developed offspring. It is concluded program occurs during cells may affect oocyte's fertilizability rather than its subsequent capacity.
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