The Block of Central Vasopressin V1 but not V2 Receptors Suppresses Grooming Behavior and Hypothermia Induced by Intracerebroventricular Vasopressin in Male Rats

作者: F Drago , M Stanciu , S Salehi , U Scapagnini

DOI: 10.1016/S0196-9781(97)00203-9

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摘要: The role of central vasopressin V1 receptors in grooming behavior induced by and oxytocin was studied male rats the Wistar strain. intracerebroventricular (ICV) injection (3 micrograms/5 microliters) hypothermia enhanced novelty-induced behavior. Enhanced but not also ICV microliters). administration a selective receptor antagonist prevented stimulating action on its hypothermic effect. V2 failed to affect vasopressin-induced An increase core temperature observed oxytocin-injected animals pretreated with antagonist. Furthermore, pretreatment did oxytocin. These results suggest that enhancement influence thermoregulation are differently regulated for

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