p53 Codon 72 Polymorphism and Gastric Cancer Risk in a Chinese Han Population
作者： Yong Zhou , Ni Li , Wen Zhuang , Xiaoting Wu
关键词:
摘要: Background: Studies investigating the association between p53 codon 72 polymorphism and gastric cancer risk report conflicting results. Our recent meta-analysis suggests that may be associated with among Asians. Aim: The objective of this study was to investigate in Chinese Han patients. Methods: We extracted peripheral blood samples from 150 patients control subjects. Polymerase chain reaction-restriction fragment length analysis performed detect these Results: Patients had a significantly lower frequency Arg/Arg (odds ratio [OR] = 0.48, 95% confidence interval [95% CI] = 0.28, 0.80; p = 0.005) than cardia higher Pro/Pro (OR = 2.26, CI = 1.12, 4.55; p = 0.02) those noncardia ...
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