摘要: Clinicians historically have considered psychomotor abnormalities as para mount features for the diagnosis of affective disorders. Nelson and Charney [1] reviewed 95 studies to determine distinctive symptoms major depressive disorder They found that retardation was at or near top most lists Overall associates [2], Kendell [3], Faykel colleagues [4,5], each identified motor one symptom useful both classification prediction treatment responses. More than half a century ago, Adolf Meyer [6] stated acceleration is striking feature associated with mania, this observation still accepted. Both DSM-III [7] Research Diagnostic Criteria [8] list agitation among items necessary depression mania.