Nucleic acids encoding sodium channel scn1a alpha subunit proteins and mutations associated with epilepsy
作者： Ronald G. Lafrenière , Daniel Rochefort , Guy A. Rouleau
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摘要: The present invention relates to epilepsy. More particularly, the idiopathic generalized epilepsy (IGE) and identification of three genes mapping chromosome 2, which show mutations in patients with further nucleic acid sequences, protein sequences these loci (SCNA) use thereof assess, diagnose, prognose or treat epilepsy, predict an epileptic individual's response medication identify agents modulate function SCNA. also provides screening assays using SCN1A, SCN2A and/or SCN3A can compounds have therapeutic benefit for related neurological disorders.
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