作者: Yong Huang , Viresh H. Rawal
DOI: 10.1021/JA0267627
关键词:
摘要: We report the first examples of hydrogen-bond-promoted acceleration hetero-Diels-Alder reactions and use such catalysis for simple, unactivated ketones. Several spiro-fused dihydropyans were synthesized in good yields using this procedure. This activation protocol represents an attractive operationally simple alternative to conventional, Lewis acid catalysis.