Causes and impact of specimen rejection in a clinical chemistry laboratory

摘要: Abstract Background Pre-analytical errors necessitate specimen rejection and negatively affect patient safety. Our purpose was to investigate the factors leading its impact. Methods Specimen rejections in a clinical chemistry laboratory during 1-year period were reviewed retrospectively analyzed for frequency, cause, circumstances, Results Of 837,862 specimens received, 2178 (0.26%) rejected. The most common reasons contamination ( n  = 764, 35.1%), inappropriate collection container/tube  = 330, 15.2%), quantity not sufficient (QNS)  = 329, 15.1%), labeling  = 321, 14.7%), hemolyzed  = 205, 9.4%), clotted  = 203, 9.3%). analytes often affected glucose  = 192, 8.8%); calcium  = 152, 7.0%), magnesium  = 148, 6.8%), potassium  = 137, 6.3%), creatinine  = 100, 4.6%), blood urea nitrogen  = 97, 4.4%). Outpatient service draw by phlebotomists associated with low rates (536/493,501 or 0.11% 368/586,503 0.06%, respectively). Recollection due increased turnaround time an average of 108 min. total cost recollection around $43,210 USD $21.9 USD. Conclusions are remediable improved training quality assurance measures. Policies procedures specific collection, transportation, preparation should be strictly followed.