Progesterone-associated increase in ERP amplitude correlates with an improvement in performance in a spatial attention paradigm

摘要: Ovarian sex hormones modulate neuronal circuits not directly involved in reproductive functions. In the present study, we investigated whether endogenous fluctuations of estradiol and progesterone during menstrual cycle are associated with early cortical processing stages a cued spatial attention paradigm. EEG was monitored while young women responded to acoustically visual stimuli. Women large mean amplitude event-related potential (ERP) (80–120 ms following stimuli) faster luteal women, ERP as well alpha amplitude, an indicator attentional modulation, correlated positively progesterone. Further, cerebral asymmetry frequency band target presentation restricted women. Critically, follicular slower right hemifield compared left targets. late or did detect disadvantage. Progesterone negatively RTs Therefore, whereas our behavioral data indicate functional recording reveal physiological hemisphere We assume that progesterone-associated enhancement synchronization synaptic activity improves categorization targets