作者: Jonathan Michael Blackburn , Michael Evans , Sriram Krishnan , Christa Lynn Brosseau
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摘要: An aptamer-based SERS detection technique that directly monitors an aptamer-analyte capture event by generating spectroscopic information regarding the identity of analyte has been bound to aptamer from a complex biological sample. A reproducible spectrum is measured for formed on metal surface and this spectral used identify specific optionally also quantify in sample, thus enabling discrimination between true false positives quantitative assays samples. In one embodiment attached surrounded self-assembled monolayer (SAM) amphiphilic molecules. alternative coated with SAM molecules SAM.