Monte Carlo and experimental internal radionuclide dosimetry in RANDO head phantom

摘要: Monte Carlo techniques are widely employed in internal dosimetry to obtain better estimates of absorbed dose distributions from irradiation sources medicine. Accurate 3D would be useful for risk assessment inducing deterministic and stochastic biological effects both therapeutic diagnostic radiopharmaceuticals nuclear The goal this study was experimentally evaluate the use Geant4 application tomographic emission (GATE) package using head portion RANDO phantom. GATE (version 6.1) used create a voxel model human phantom computed tomography (CT) images. Matrix dimensions consisted 319 × 216 × 30 voxels (0.7871 × 0.7871 × 5 mm3). Measurements were made thermoluminescent dosimeters (TLD-100). One rod-shaped source with 94 MBq activity 99mTc positioned brain tissue posterior part slice number 2. results simulation compared measured mean per cumulative (S value). Absorbed also calculated each digital volume histograms (DVHs) analyze absolute relative doses data. S-values by TLD methods showed significant correlation (correlation coefficient, r 2 ≥ 0.99, p < 0.05) other. maximum percentage differences ≤14 % most cases. DVHs demonstrated decrease along direction movement toward lower slices Based on obtained Carlopackage it can deduced that complete study, imaging map calculation, is possible execute single framework.