Myocardial infarction in a patient with thrombotic thrombocytopenic purpura

作者: Sumeesh Dhawan , Tahir Tak

DOI: 10.1016/J.IJCARD.2003.04.039

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摘要: Abstract A 63-year-old male with a prior history of thrombotic thrombocytopenic purpura was admitted sudden onset syncope. He denied chest pain. His initial blood chemistries were consistent acute relapse as indicated by microangiopathic hemolytic anemia and thrombocytopenia. The patient had evidence myocardial injury elevation cardiac enzymes. 12-lead electrocardiogram demonstrated ST (up to 5 mm) in leads V 2 6 . treated plasma exchange fresh frozen addition nitroglycerin, metoprolol prednisone tapering dose. After reviewing the literature, we believe that etiology damage remains elusive, but may be secondary an autoimmune phenomenon resulting microthrombosis myocarditis. We unable find any documentation about specific treatment such patients. Further studies are awaited regarding appropriate patients electrocardiographic changes.

参考文章(6)
Larry A. Sonna, Frederick J. Schoen, Richard J. Benjamin, Scott H. Podolsky, Artur Zembowicz, Massive myocardial necrosis in thrombotic thrombocytopenic purpura: a case report and review of the literature. Archives of Pathology & Laboratory Medicine. ,vol. 123, pp. 937- 940 ,(1999) , 10.1043/0003-9985(1999)123<0937:MMNITT>2.0.CO;2
P ECKART, M GUILLOT, M JOKIC, P MARAGNES, B BOUDAILLIEZ, J PALCOUX, V DESVIGNES, Atteinte cardiaque au cours du syndrome hémolytique et urémique typique Archives De Pediatrie. ,vol. 6, pp. 430- 433 ,(1999) , 10.1016/S0929-693X(99)80226-7
C. Richard Conti, Thrombolytic therapy in thrombocytopenic patients Clinical Cardiology. ,vol. 18, pp. 299- 300 ,(1995) , 10.1002/CLC.4960180603
REN L. RIDOLFI, The Heart and Cardiac Conduction System in Thrombotic Thrombocytopenic Purpura Annals of Internal Medicine. ,vol. 91, pp. 357- 363 ,(1979) , 10.7326/0003-4819-91-3-357
Sharda Gupta, James W. Funkhouser, Treatment of thrombotic thrombocytopenic purpura with plasma exchange: five cases. Journal of Clinical Apheresis. ,vol. 2, pp. 195- 199 ,(1984) , 10.1002/JCA.2920020209
van den Berg B, Kros Jm, Siersema Pd, Cardiac manifestations of thrombotic thrombocytopenic purpura. Netherlands Journal of Medicine. ,vol. 35, pp. 100- ,(1989)