Increased levels of vascular endothelial growth factor in the aqueous humor of patients with diabetic retinopathy.
作者： KocaboraM Selim , Durmaz Sahan , Taskapili Muhittin , Cekic Osman , Ozsutcu Mustafa
关键词:
摘要: Purpose: This study aims to investigate the levels of aqueous vascular endothelial growth factor (VEGF) in diabetic patient groups comparison normal subjects, and correlate elevated VEGF with severity retinopathy (DR). Materials Methods: Aqueous samples were obtained from 78 eyes 74 patients undergoing intraocular surgery they examined by enzyme-linked immunosorbent assay. Color photographs, optical coherence tomography scans, fluorescein angiography used evaluate preoperatively. Results: A strong statistical correlation was found exist between level DR ( P < 0.001), whereas, a control group without not significantly different = 0.985). proliferative (PDR) as compared (NDR) nonproliferative (NPDR) 0.001). The higher active PDR than those quiescent On other hand, statistically insignificant 0.065) presence macular edema NPDR group. Conclusions: humor that eyes. had along difference edema.
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