Tumour-directed microenvironment remodelling at a glance.

摘要: The tissue microenvironment supports normal function and regulates the behaviour of parenchymal cells. Tumour cell behaviour, on other hand, diverges significantly from that their counterparts, rendering hostile to tumour To overcome this problem, tumours can co-opt remodel facilitate growth spread. This involves modifying both biochemistry biophysics produce a microenvironment. In Cell Science at Glance article accompanying poster, we outline key processes by which epithelial influence establishment As is populated genetically cells, discuss how controlling significant challenge vulnerability for tumours. Finally, review new insights into tumour-microenvironment interactions has led current consensus these may be targeted as novel anti-cancer therapies.