Dysembryoplastic Neuroepithelial Tumor

作者: Ana Lia Taratuto , Hugo Pomata , Gustavo Sevlever , Guillermo Gallo , Jorge Monges

DOI: 10.1097/00006123-199503000-00005

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摘要: Overtreatment by radiotherapy and/or chemotherapy for central nervous system tumors in infancy and childhood may be deleterious, so the recognition of surgically curable clinicopathological entities is mandatory. The dysembryoplastic neuroepithelial tumor a complex multinodular lesion consisting glial nodules, associated with specific glioneuronal element focal cortical dysplasia, occurring young patients presenting intractable, mostly partial, seizures without neurological deterioration. We report on 14 patients; 9 were from series 600 pediatric intracranial studied at single institution 1988 to 1993, 5 referred other hospitals. Six frontal, six temporal, one was parietal, occipitoparietal. Computed tomographic scans disclosed hypodense lesions cystic appearances 4 slight postcontrast enhancements only 2 patients, whereas magnetic resonance imaging, available 7 showed hypointense T1-weighted images hyperintense T2-weighted images. Deformities overlying cranium also observed five patients. age range time surgery (excluding 20-year-old male patient who underwent main hospital) 2.6 13 years, mean 6.68 years. female ratio 10:4, duration symptoms 0.2 6 years.(ABSTRACT TRUNCATED AT 250 WORDS)

参考文章(20)
Cervós-Navarro J, Skotzek-Konrad B, Gottschalk J, Goebel S, Korves M, Dysembryoplastic neuroepithelial micro-tumor in a 75-year-old patient with long-standing epilepsy. Clinical Neuropathology. ,vol. 12, pp. 175- 178 ,(1993)
S. Y. Leung, E. Gwi, H. K. Ng, C. F. Fung, K. Y. Yam, Dysembryoplastic neuroepithelial tumor: A tumor with small neuronal cells resembling oligodendroglioma The American Journal of Surgical Pathology. ,vol. 18, pp. 604- 614 ,(1994) , 10.1097/00000478-199406000-00004
E. Hoppe-Hirsch, D. Renier, A. Lellouch-Tubiana, C. Sainte-Rose, A. Pierre-Kahn, J. F. Hirsch, Medulloblastoma in childhood: progressive intellectual deterioration Childs Nervous System. ,vol. 6, pp. 60- 65 ,(1990) , 10.1007/BF00307922
Leopold G. Koss, Bogdan Czerniak, Fritz Herz, Robert P. Wersto, Flow cytometric measurements of DNA and other cell components in human tumors: a critical appraisal. Human Pathology. ,vol. 20, pp. 528- 548 ,(1989) , 10.1016/0046-8177(89)90244-X
Eva Karamitopoulou, Elias Perentes, Maria Melachrinou, Theodore Maraziotis, Proliferating cell nuclear antigen immunoreactivity in human central nervous system neoplasms. Acta Neuropathologica. ,vol. 85, pp. 316- 322 ,(1993) , 10.1007/BF00227728
Takanori Hirose, Bernd W. Scheithauer, M Beatriz S. Lopes, Scott R. Vandenberg, Dysembryoplastic Neuroepithelial Tumor (DNT): An Immunohistochemical and Ultrastructural Study Journal of Neuropathology and Experimental Neurology. ,vol. 53, pp. 184- 195 ,(1993) , 10.1097/00005072-199403000-00010
S. Khoshyomn, H. Maier, T. Morimura, K. Kitz, H. Budka, Immunostaining for proliferating cell nuclear antigen: its role in determination of proliferation in routinely processed human brain tumor specimens. Acta Neuropathologica. ,vol. 86, pp. 582- 589 ,(1993) , 10.1007/BF00294296
Stanley L. Robbins, Ramzi S. Cotran, Pathologic basis of disease ,(1974)
George L. Wied, Peter H. Bartels, Marluce Bibbo, Harvey E. Dytch, Image analysis in quantitative cytopathology and histopathology. Human Pathology. ,vol. 20, pp. 549- 571 ,(1989) , 10.1016/0046-8177(89)90245-1
Shunji Nishio, Iwao Takeshita, Yoichi Kaneko, Masashi Fukui, Cerebral neurocytoma. A new subset of benign neuronal tumors of the cerebrum. Cancer. ,vol. 70, pp. 529- 537 ,(1992) , 10.1002/1097-0142(19920715)70:2<529::AID-CNCR2820700225>3.0.CO;2-0