Helicobacter pylori (H. pylori) infection in coronary artery disease: influence of H. pylori eradication on coronary artery lumen after percutaneous transluminal coronary angioplasty. The detection of H. pylori specific DNA in human coronary atherosclerotic plaque.

摘要: We tested the hypothesis that intermittent apneas performed by awake subjects simulate obstructive sleep apnea (OSA) and change dynamic complexity of cardiovascular control system repetitive short time stimulation arterial chemoreceptors. Correlation dimension (CD) reccurent plot quantification calculated as ratio % determinism versus recurrence (RDR) were used.as indices chaotic dynamics. Thirty three normotensive mean age 21,58 +/- 4,1 10 voluntary 1 min. each separated min free breathing period. Systolic (SYS), diastolic (DIAS) blood pressure was continuously recorded finger volume clamp. Stroke (SV) estimated pulse analysis. Cardiac output (CO) total peripheral resistance (TPR) Portapress system. inter-beat interval (IBI) measured from R-R intervals ECG. Standard deviation (SD), an index linear variability, in epoch. Dynamics variables computed subject during 20 rest (C), apneas, each, (A), recovery (R). In A period CD all circulatory significantly reduced RDR augmented. 23 out 33 decreased nonlinear dynamics TPR carried over to R. contrast, SD increased A. conclusion, brief chemoreflex stimulations increase decrease behaviour autonomic system, presumably inhibition some regulatory loops such baroreflex, less vital for survival at oxygen deprivation. Reduced could be implicated mechanism hypertension linked with OSA.