Bronchoalveolar Lavage and Transbronchial Biopsy for the Diagnosis of Pulmonary Infections in the Acquired Immunodeficiency Syndrome

作者: Courtney Broaddus , Michael D Dake , Michael S Stulbarg , WALTER BLUMENFELD , W KEITH HADLEY

DOI: 10.7326/0003-4819-102-6-747

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摘要: The efficacy of bronchoalveolar lavage and transbronchial biopsy in diagnosing lung infection was determined 276 fiberoptic bronchoscopic examinations done on 171 patients with known or suspected acquired immunodeficiency syndrome. Of 173 pathogens (Pneumocystis carinii, cytomegalovirus, Mycobacterium avium-intracellulare, Cryptococcus neoformans, M. tuberculosis, Coccidioides immitis, Histoplasma capsulatum) identified during the initial evaluation subsequent month, examination detected 166 (96%). Bronchoalveolar had sensitivities 86% 87%, respectively. When bronchoscopy included both biopsy, yield for all 98% sensitivity P. carinii infections 100%. Follow-up at least 3 weeks after failed to detect any additional false-negative results. Fiberoptic is extremely accurate detection syndrome, especially when are combined. In high risk complications from sufficiently be used alone.

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