A survey of single-molecule techniques in chemical biology.
作者： Peter V. Cornish , Taekjip Ha
DOI: 10.1021/CB600342A
关键词:
摘要: Single-molecule methods have revolutionized scientific research by rendering the investigation of once-inaccessible biological processes amenable to inquiry. Several more established techniques will be emphasized in this Review, including single-molecule fluorescence microscopy, optical tweezers, and atomic force which been applied many diverse processes. Serving as a taste all exciting currently underway, recent examples discussed translocation RNA polymerase, myosin VI walking, protein folding, enzyme activity. We end providing an assessment what future holds, that are development.
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