Importance of screening for synchronous malignant neoplasms in patients with hepatocellular carcinoma: impact of FDG PET/CT

作者: Atsushi Hiraoka , Masashi Hirooka , Hironori Ochi , Yohei Koizumi , Yuko Shimizu

DOI: 10.1111/LIV.12161

关键词:

摘要: Background & Aim Synchronous neoplasms (SNs) are occasionally found in hepatocellular carcinoma (HCC). We examined such cases and the efficacy of 18-fluoro-2-deoxyglucose positron-emission tomography computed (PET/CT), retrospectively. Materials Methods We investigated 687 naive HCC, who were admitted to our hospitals, encountered from October 2006 December 2010 evaluated clinical backgrounds. All study protocols, was approved by Institutional Ethics Committee. The usefulness detecting SNs PET/CT 234 patients underwent (PET group) 453 (non-PET same period. noted presence SNs, defined as primary extrahepatic malignant within 1 year diagnosis HCC. Results SNs observed 48 (54 tumours, 7.0%). detected 18, which 7.7% PET group. detection rate for increased 11.1% (26/234) group using together with upper gastrointestinal endoscopy routine enhanced CT greater than that non-PET (22/453, 4.9%) (P < 0.001). Conclusion SNs pointed out more frequently (11.1% vs. 4.9%). FDG can enhance ability HCC.

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