IFN-α and IL-18 synergistically enhance IFN-γ production in human NK cells: differential regulation of Stat4 activation and IFN-γ gene expression by IFN-α and IL-12

作者: Sampsa Matikainen , Auli Paananen , Minja Miettinen , Masashi Kurimoto , Tuomo Timonen

DOI: 10.1002/1521-4141(200107)31:7<2236::AID-IMMU2236>3.0.CO;2-G

关键词:

摘要: … We show that Stat4 activation is transient in cells stimulated with IFN-α , whereas IL-12 … anti-Stat4 Ab, because the amount of primary NK cells obtained by magnetic-bead purification is …

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