Are visceral adiposity index and lipid accumulation product reliable indices for metabolic disturbances in patients with type 2 diabetes mellitus

摘要: Background Visceral adiposity index (VAI) and Lipid accumulation product (LAP) are novel visceral indexes, proposed for the evaluation of cardiometabolic risk in adult population. Considering contradictory results obtained from many studies so far, we aimed to examine potential benefit applicability VAI LAP, over simple anthropometric indices traditional lipid parameters individuals with type 2 diabetes mellitus (DM2). Methods A total 180 DM2 (of them 50% females) 119 controls who volunteered participate this cross-sectional study were enrolled. Anthropometric biochemical parameters, as well blood pressure obtained. LAP calculated. Results Multivariate logistic regression analysis showed that high-density lipoprotein cholesterol (HDL-c), (P<.001), waist circumference (WC), (P=.027), age (P=.001), hypolipemic therapy (P=.024), (P=.005) independent predictors adjusted models. In Receiver Operating Characteristic curve analysis, used discriminate subjects those did not have it, good accuracy applied procedures was only achieved models which consisted (Body mass index, WC, HDL-c, triglycerides) (WC, indexes equations, respectively [Area under (AUC)=0.819 AUC=0.800, respectively], but (AUC=0.781) (AUC=0.784) themselves. Conclusion Visceral may be better than enter its equation prediction.