Rapid point-of-care CD4 testing at mobile units and linkage to HIV care: an evaluation of community-based mobile HIV testing services in South Africa

作者: Rosa Sloot , Mary T. Glenshaw , Margaret van Niekerk , Sue-Ann Meehan

DOI: 10.1186/S12889-020-08643-3

关键词:

摘要: Mobile HIV testing services (HTS) are effective at reaching undiagnosed people living with HIV. However, linkage to care from mobile HTS is often poor, ranging 10 60%. Point-of-care (POC) CD4 has shown increase retention in health facilities, but little evidence exists about their use HTS. This study assessed the feasibility of POC test implementation and investigated among clients accepting a community-based retrospective used routinely collected data who utilized City Cape Town Metropolitan district, South Africa between December 2014 September 2016. A was offered all an positive diagnosis during this period, cell count provided test. Random effects logistic regression assess factors associated uptake self-reported Models were adjusted for sex, age, previous done, tuberculosis status year diagnosis. One thousand three hundred twenty-five Thirty-nine seven ninety utilizing tested (3%). 51% (679/1325) accepted The age group highest proportion 50+ years (60%). Females less likely accept than males (odds ratio = 0.7, 95%CI = 0.6–0.8). Median 429 cells/μl (interquartile range = 290–584). Among 679 test, 491 (72%) linked care. not Our findings suggest that can identify early infection, show high result Future research should acceptance impact comparison alternative strategies engage

参考文章(26)
N. Mohlabane, K. Zuma, S. Moyo, M. Mabaso, L. Simbayi, S. Ramlagan, E. Marinda, C. Dietrich, I. Naidoo, A. North, South African National HIV Prevalence, HIV Incidence, Behaviour and Communication Survey, 2005 ,(2008)
IV Bassett, S Regan, P Luthuli, H Mbonambi, B Bearnot, A Pendleton, M Robine, D Mukuvisi, H Thulare, RP Walensky, KA Freedberg, E Losina, B Mhlongo, Linkage to care following community-based mobile HIV testing compared with clinic-based testing in Umlazi Township Durban South Africa. Hiv Medicine. ,vol. 15, pp. 367- 372 ,(2014) , 10.1111/HIV.12115
Robin Wood, Stephen D. Lawn, Judy Caldwell, Richard Kaplan, Keren Middelkoop, Linda-Gail Bekker, Burden of new and recurrent tuberculosis in a major South African city stratified by age and HIV-status. PLOS ONE. ,vol. 6, ,(2011) , 10.1371/JOURNAL.PONE.0025098
Darshini Govindasamy, Nienke van Schaik, Katharina Kranzer, Robin Wood, Catherine Mathews, Linda-Gail Bekker, Linkage to HIV care from a mobile testing unit in South Africa by different CD4 count strata. Journal of Acquired Immune Deficiency Syndromes. ,vol. 58, pp. 344- 352 ,(2011) , 10.1097/QAI.0B013E31822E0C4C
Ingrid V. Bassett, Susan Regan, Hlengiwe Mbonambi, Jeffrey Blossom, Stacy Bogan, Benjamin Bearnot, Marion Robine, Rochelle P. Walensky, Bright Mhlongo, Kenneth A. Freedberg, Hilary Thulare, Elena Losina, Finding HIV in Hard to Reach Populations: Mobile HIV Testing and Geospatial Mapping in Umlazi Township, Durban, South Africa Aids and Behavior. ,vol. 19, pp. 1888- 1895 ,(2015) , 10.1007/S10461-015-1012-3
Bruce A. Larson, Kathryn Schnippel, Buyiswa Ndibongo, Thembisile Xulu, Alana Brennan, Lawrence Long, Matthew P. Fox, Sydney Rosen, Rapid point-of-care CD4 testing at mobile HIV testing sites to increase linkage to care: an evaluation of a pilot program in South Africa. Journal of Acquired Immune Deficiency Syndromes. ,vol. 61, ,(2012) , 10.1097/QAI.0B013E31825EEC60
M. J. Siedner, C. K. Ng, I. V. Bassett, I. T. Katz, D. R. Bangsberg, A. C. Tsai, Trends in CD4 Count at Presentation to Care and Treatment Initiation in Sub-Saharan Africa, 2002–2013: A Meta-analysis Clinical Infectious Diseases. ,vol. 60, pp. 1120- 1127 ,(2014) , 10.1093/CID/CIU1137
Sue-Ann Meehan, Pren Naidoo, Mareli M Claassens, Carl Lombard, Nulda Beyers, Characteristics of clients who access mobile compared to clinic HIV counselling and testing services: a matched study from Cape Town, South Africa BMC Health Services Research. ,vol. 14, pp. 658- 658 ,(2014) , 10.1186/S12913-014-0658-2
Leigh F. Johnson, Joel Mossong, Rob E. Dorrington, Michael Schomaker, Christopher J. Hoffmann, Olivia Keiser, Matthew P. Fox, Robin Wood, Hans Prozesky, Janet Giddy, Daniela Belen Garone, Morna Cornell, Matthias Egger, Andrew Boulle, , Life Expectancies of South African Adults Starting Antiretroviral Treatment: Collaborative Analysis of Cohort Studies PLoS Medicine. ,vol. 10, pp. e1001418- ,(2013) , 10.1371/JOURNAL.PMED.1001418