New-Onset Lupus Nephritis in a Kidney Transplant Recipient With Cystinosis—Differential Diagnosis With Cysteamine-Induced Lupus: Case Report

摘要: A case of lupus nephritis in an adult female kidney transplant recipient with cystinosis under cysteamine therapy is reported. Previous reports new-onset cystinotic patients have focused a possible relationship therapy, but no obvious pathophysiological association has been disclosed. The authors present 19-year-old admitted for acute allograft dysfunction, clinical and immunologic manifestations nephritis. Cysteamine was considered as potential cause drug-induced lupus, we temporarily interrupted this drug. picture, the negativity antihistone antibodies, nondisappearance antinuclear antibodies after discontinuation drug, stability resuming suggested that underlying mechanism unrelated to This may be first report cystinosis. Clinicians should aware autoimmune abnormalities