The first case of postpartum acquired hemophilia A in Korea.

摘要: Acquired hemophilia A (AHA) is a rare coagulopathy caused by autoantibodies to coagulation factor VIII (FVIII). Most patients with AHA have been previously healthy; however, variety of morbidities associated the condition including pregnancy. 40-yr-old woman visited our institution extensive hematoma on right hip area. Her medical history revealed no personal or familial bleeding diathesis. tests showed markedly prolonged aPTT (117 sec), decreased level FVIII activity (0.4%) and high-titer inhibitor (77 BU). Collectively, she was diagnosed as having postpartum treated bypassing agents corticosteroids. normalized 174 th day negative conversion 224 day. This first case in Korea. Timely diagnosis management can reduce morbidity mortality this potentially life-threatening condition.