High prevalence of hypovitaminosis D and secondary hyperparathyroidism in elders living in nonprofit homes in South Brazil.

摘要: Objectives Hypovitaminosis D (HD) and secondary hyperparathyroidism (SHP) are common in elders, many factors could contribute to them. The objectives of this study were estimate the prevalence HD, SHP, its associated factors, individuals living nonprofit homes for elders south Brazil. Design Cross-sectional study. Methods Serum 25-hydroxyvitamin 25(OH)D, intact parathyroid hormone (PTH), total calcium, phosphorus, alkaline phosphatase, magnesium, creatinine, albumin levels measured late spring, November, 2005. presence potentially related with HD SHP—age, sex, weight, height, skin phototype, sun exposure, exercise, smoking, use ≤5 medications or diuretics alcohol, daily calcium ingestion. Results 102 subjects age 77.8 ± 9.0 included was found 85.7% SHP 53% subjects. estimated ingestion 720 mg. There no association between serum 25(OH)D any risk evaluated. correlated PTH (r = −0.358, P 0.000), 0.306, 0.002), 0.253, 0.011) levels. In univariate analysis, positively (P 0.006), female sex (0.007); negatively sunlight exposure 0.020), GFR Ln25(OH)D 0.024). After multivariate model adjustment, [OR 1.09 (CI 1.01–1.18); 0.024], 0.92 0.08–0.74); 0.013], 0.96 0.92–0.99); hydrochlorothiazide treatment 7.63 1.67–34.9); 0.008] independently SHP. Conclusions highly prevalent old-age homes. No associations established low levels; however, age, GFR, use.