On the nature of the initial luteotropic stimulus of pregnancy in the Rhesus monkey.

摘要: Implantation is associated with a major but short-lived increase in progesterone secretion at time when circulating levels are falling the non-fertile menstrual cycle. The working hypothesis that this luteotropic stimulus of trophoblastic origin has been tested by administering human chorionic gonadotropin (HCG) to non-pregnant animals during late luteal phase Daily intramuscular injections HCG (17.5–500 IU) were followed precipitous rise plasma concentration was not sustained despite continued hormone administration. pattern observed treated 25 IU per day closely resembles normally immediate post-implantation period. refractoriness corpus luteum exogenous gonadotropic stimulation accord finding decline surge occurs face rising tide chorioni...