The use of serum creatine phosphokinase in genetic counseling for Duchenne muscular dystrophy. II. Review of methods of assay and factors which may be relevant in the interpretation of serum creatine phosphokinase activity.

摘要: Abstract Several methods of CPK assay are compared and some factors which may affect serum activity be relevant to genetic counseling for carriers DMD discussed. We conclude from the published material that, practical purposes, normal daily activity, stage menstrual cycle use contraceptive pill do not activity. is higher in males than females Blacks Whites, these should considered choice controls studies on this subject. lowered during pregnancy; it appears rise as day progresses; effect advancing age yet clear. Although other diagnosing have been suggested, present will probably remain principal corroborative test purpose, various its interpretation.