Working memory is more sensitive than declarative memory to the acute effects of corticosteroids: a dose-response study in humans.

作者: Richard L. Hauger , Sonia J. Lupien , Christian J. Gillin

DOI: 10.1037//0735-7044.113.3.420

关键词:

摘要: The effects of various doses (40 microg/kg/hr, 300 600 microg/kg/hr or placebo) hydrocortisone on tasks assessing working and declarative memory function were measured in 4 groups 10 young men. During the infusion, participants given an item-recognition task, a paired-associate continuous performance task used to control possible concomitant corticosteroids vigilance. results revealed significant acute highest dose function, without any effect arousal-vigilance performance. These suggest that is more sensitive than elevations corticosteroids, which could explain detrimental acquisition consolidation information, as reported literature.

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