Mean platelet volume is increased in patients with hypertensive crises
作者： Mustafa Karabacak , Abdullah Dogan , Ahmet Kenan Turkdogan , Mucahit Kapci , Ali Duman
DOI: 10.3109/09537104.2013.830181
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摘要: AbstractPlatelets may be activated in hypertension (HT). Hypertensive crisis is an extreme phenotype of HT and HT-related thrombotic complications. We aimed to assess mean platelet volume (MPV) patients with hypertensive crises. This study included 215 urgency (HU) (84 male, age = 66 ± 15 years) 60 emergency (HE) (26 age = 68 ± 13 years), who were admitted the department a diagnosis Control group was composed age- sex-matched 39 normotensive patients. Blood samples withdrawn for whole blood count routine biochemical tests. Systolic pressure (BP) significantly higher HE than HU (p < 0.001). Median compared control groups [9.5 (Interquartile range, IQR: 8.7–10.1), 8.4 (IQR: 7.7–9.1), 8.3 7.7–8.7) fl, each p < 0.001, respectively). In linear regression analysis, systolic BP (...
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researchgate.net 参考文章(22)
C A J M Gaillard, J J Beutler, A H van den Meiracker, A A Kroon, B J H van den Born, A de Gooijer, Dutch guideline for the management of hypertensive crisis -- 2010 revision. Netherlands Journal of Medicine. ,vol. 69, pp. 248- 255 ,(2011)
Sunil K. Nadar, Andrew D. Blann, Sridhar Kamath, D.Gareth Beevers, Gregory Y.H. Lip, Platelet indexes in relation to target organ damage in high-risk hypertensive patients: A substudy of the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT)☆ Journal of the American College of Cardiology. ,vol. 44, pp. 415- 422 ,(2004) , 10.1016/J.JACC.2004.03.067
Joseph A. Jakubowski, Craig B. Thompson, Raymond Vaillancourt, C. Robert Valeri, Daniel Deykin, Arachidonic acid metabolism by platelets of differing size British Journal of Haematology. ,vol. 53, pp. 503- 511 ,(1983) , 10.1111/J.1365-2141.1983.TB02052.X
Ronald Wallach, Robert B. Karp, J.G. Reves, Suzanne Oparil, Lloyd R. Smith, Thomas N. James, Pathogenesis of Paroxysmal Hypertension Developing During and After Coronary Bypass Surgery: A Study of Hemodynamic and Humoral Factors American Journal of Cardiology. ,vol. 46, pp. 559- 565 ,(1980) , 10.1016/0002-9149(80)90503-2
J.F. Martin, E.A. Trowbridge, Geraldine Salmon, Julie Plumb, The biological significance of platelet volume: Its relationship to bleeding time, platelet thromboxane B2 production and megakaryocyte nuclear DNA concentration Thrombosis Research. ,vol. 32, pp. 443- 460 ,(1983) , 10.1016/0049-3848(83)90255-4
Mark J. Ault, A.Gray Ellrodt, Pathophysiological events leading to the end-organ effects of acute hypertension American Journal of Emergency Medicine. ,vol. 3, pp. 10- 15 ,(1985) , 10.1016/0735-6757(85)90227-X
Christopher J. Boos, Gareth D. Beevers, Gregory Y. H. Lip, Assessment of platelet activation indices using the ADVIATM 120 amongst 'high-risk' patients with hypertension. Annals of Medicine. ,vol. 39, pp. 72- 78 ,(2007) , 10.1080/07853890601040063
Stavroula Tsiara, Moses Elisaf, I. Anita Jagroop, Dimitri P. Mikhailidis, Platelets as predictors of vascular risk: is there a practical index of platelet activity? Clinical and Applied Thrombosis-Hemostasis. ,vol. 9, pp. 177- 190 ,(2003) , 10.1177/107602960300900301
P. M. W. Bath, R. J. Butterworth, Platelet size: measurement, physiology and vascular disease Blood Coagulation & Fibrinolysis. ,vol. 7, pp. 157- 161 ,(1996) , 10.1097/00001721-199603000-00011
Erkan Coban, Gokhan Yazicioglu, Ali Berkant Avci, Ferhat Akcit, The mean platelet volume in patients with essential and white coat hypertension. Platelets. ,vol. 16, pp. 435- 438 ,(2005) , 10.1080/09537100500163572