Peritoneal cavity lavage reduces the presence of mitochondrial damage associated molecular patterns in open abdomen patients.

作者: Patricia A. Martinez-Quinones , Cameron G. McCarthy , Caleb J. Mentzer , Camilla F. Wenceslau , Steven B. Holsten

DOI: 10.1097/TA.0000000000001676

关键词:

摘要: BACKGROUNDMitochondrial damage-associated molecular patterns (mtDAMPs), such as mitochondrial DNA and N-formylated peptides, are endogenous molecules released from tissue after traumatic injury. mtDAMPs potent activators of the innate immune system. They have similarities with bacteria, which al

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