Early Predictors of Severity in Acute Lower Intestinal Tract Bleeding

作者: Lisa L. Strate , E. John Orav , Sapna Syngal

DOI: 10.1001/ARCHINTE.163.7.838

关键词:

摘要: Background Identification of high-risk patients with lower intestinal tract bleeding (LIB) is challenging, and prognostic factors have not been clearly defined. The aim this study was to determine risk for severe acute LIB. Methods A total 252 consecutive admitted LIB were identified. Data collected on 24 clinical available in the first 4 hours evaluation. outcome bleeding, which defined as continued within hospitalization (transfusion ≥2 units blood and/or hematocrit decrease ≥20%) recurrent after stability (additional transfusions, further ≥20%, or readmission 1 week discharge). Results Severe occurred 123 (49%). Independent correlates follows: heart rate, ≥100/min (odds ratio [OR], 3.67; 95% confidence interval [CI], 1.78-7.57); systolic pressure, ≤115 mm Hg (OR, 3.45; CI, 1.54-7.72); syncope 2.82; 1.06-7.46); nontender abdominal examination 2.43; 1.22-4.85); per rectum during evaluation 2.32; 1.28-4.20); aspirin use 2.07; 1.12-3.82); more than 2 active comorbid conditions 1.93; 1.08-3.44). Conclusion Clinical data initial can be used identify at LIB, who may benefit most from urgent intervention.

参考文章(33)
Dennis M. Jensen, Gustavo A. Machicado, Colonoscopy for diagnosis and treatment of severe lower gastrointestinal bleeding. Routine outcomes and cost analysis. Gastrointestinal Endoscopy Clinics of North America. ,vol. 7, pp. 477- 498 ,(1997) , 10.1016/S1052-5157(18)30301-5
MEL C. WILCOX, SCOTT W. CLARK, Causes and outcome of upper and lower gastrointestinal bleeding: the Grady Hospital experience. Southern Medical Journal. ,vol. 92, pp. 44- 50 ,(1999) , 10.1097/00007611-199901000-00008
Fred E. Silverstein, David A. Gilbert, Francis J. Tedesco, Nancy K. Buenger, Joyce Persing, The National ASGE Survey on Upper Gastrointestinal Bleeding: II. Clinical prognostic factors Gastrointestinal Endoscopy. ,vol. 27, pp. 80- 93 ,(1981) , 10.1016/S0016-5107(81)73156-0
Stanley Lemeshow, David W. Hosmer, Applied Logistic Regression ,(1989)
Bradley Efron, Gail Gong, A Leisurely Look at the Bootstrap, the Jackknife, and Cross-Validation The American Statistician. ,vol. 37, pp. 36- 48 ,(1983) , 10.1080/00031305.1983.10483087
Antonio Caos, Kent G. Benner, James Manier, Denis M. McCarthy, Larry D. Blessing, Ronald M. Katon, Howard K. Gogel, Colonoscopy After Golytely Preparation in Acute Rectal Bleeding Journal of Clinical Gastroenterology. ,vol. 8, pp. 46- 49 ,(1986) , 10.1097/00004836-198602000-00010
Y. Oshita, Y. Okazaki, T. Takemoto, K. Kawai, What are the signs of recent hemorrhage, and what do they mean? Criteria for massive bleeding. Endoscopy. ,vol. 18, pp. 11- 14 ,(1986) , 10.1055/S-2007-1018419
D. Provenzale, R.S. Sandler, D.R. Wood, S.L. Levinson, J.T. Frakes, R.B. Sartor, A.L. Jackson, Η.B. Kinard, E.H. Wagner, D.W. Powell, Development of a scoring system to predict mortality from upper gastrointestinal bleeding The American Journal of the Medical Sciences. ,vol. 294, pp. 26- 32 ,(1987) , 10.1097/00000441-198707000-00004