Membrane Structure and Dynamics by NMR. Part 1: Effect of Cyclopropane Rings, Double Bonds and Sterols on the Structure and Dynamics of Phospholipid Membranes

摘要: It is nowadays well recognized that many important biophysical events occur at the biological membrane level. The can regulate, for instance, vectorial transport of nutrients, waste, and exogenous components such as drugs. also provide a site cell-specific antigens hormone receptors. Unfortunately, molecular mehanisms giving rise to are not always characterized often known all. This poor level knowledge essentially resides in complexity membrane. Lipids proteins which compose indeed have wide variety chemical structures. Moreover, it appears activity closely linked relative amount each these compounds their spatial and/or temporal distribution study structure dynamics therefore potential tool understanding mechanisms occurring or