Apoptosis and some of its medical implications.

作者: J Kawiak , T Skorski , G Hoser

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摘要: The following phases of apoptosis were proposed: decisive, executive and degradation. At least two checkpoints are recognized in the process apoptosis: p53 Bcl-2/Bax protein family checkpoint protease-caspase serine protease checkpoint. Signals to from outside cell including Fas ligand interaction sphingomyelin cycle presented. Cellular morphological events DNA chain breaks, changes membrane mitochondrial membranes discussed. Some medical problems cardiology which plays an important role cancer treatment results depending on cells discussed as well.

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